Skin repair that works from within

Polynucleotides are regenerative injectables that heal and rebuild skin at a cellular level, offered by our Southport team.

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Polynucleotides in Southport

Polynucleotides are one of the most talked-about developments in regenerative skincare, and for good reason. Rather than adding volume, they work at a cellular level to repair, rebuild and strengthen the skin from within. They sit at the heart of our regenerative skin treatments and suit anyone focused on skin quality rather than shape.

Natural Results You'll Love

Regenerates from within
Polynucleotides stimulate your skin’s own repair response, boosting collagen and elastin over a course of treatments.
They target dullness, fine lines and uneven texture, leaving skin brighter, firmer and healthier looking.
They can be used on the face, under-eyes, neck and décolletage, and suit sensitive or damaged skin.

Why polynucleotides work

Polynucleotides are purified DNA fragments that act as biostimulators. Injected into the dermis, they calm inflammation and switch on the fibroblasts that build collagen and elastin, so your skin rebuilds its own structure over the following weeks. This is why results are gradual and genuinely regenerative rather than a quick plumping effect. A course builds a lasting improvement in skin health, which is why we usually recommend two or three sessions to start.

Treatment time:

30 to 40 minutes per session

Downtime:

Minimal. Small bumps or redness usually settle within 24 hours.

Why polynucleotides work

Polynucleotides are purified DNA fragments that act as biostimulators. Injected into the dermis, they calm inflammation and switch on the fibroblasts that build collagen and elastin, so your skin rebuilds its own structure over the following weeks. This is why results are gradual and genuinely regenerative rather than a quick plumping effect. A course builds a lasting improvement in skin health, which is why we usually recommend two or three sessions to start.

Treatment time:

30 to 40 minutes per session

Downtime:

Minimal. Small bumps or redness usually settle within 24 hours.

What to Expect After Your Treatment

Keep the area clean and makeup-free for the first 12 to 24 hours, avoid heat, strenuous exercise and alcohol for a day or two, and use a gentle SPF. Any small bumps or redness usually settle within a day. See our aftercare page for the full routine.

When Will I See Results?

Gradually, with brightness early and full effect over several weeks

How Long Can I Enjoy My Results?

6 to 12 months, maintained with top-ups

How Many Treatments Will I Need?

Course of 2 to 3 sessions, 3 to 4 weeks apart

Is This Right For Me?

Suitable for adults over 18 looking to improve skin quality rather than add volume. It is not carried out during pregnancy or breastfeeding, or over active skin infections. We check your suitability at consultation and treat only over-18s.
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Lottie Hawthorn
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I would 100% recommend Rachel, she was very gentle whilst doing the treatment as well as being so welcoming and friendly on my first visit. The results where amazing and lasted months! 🤩
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Aimee Goertz
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Highly rate Rachael and her skin lounge. Rachael ensures to fully understand how you like to feel after your Botox before taking any action. I walked away feeling fabulous and knowing how much Racheal cares about how her clients look and feel! Thank you 🙏
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Jennie Hoskins
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I can’t recommend Rachel highly enough. This was my very first appointment with Rachel and it certainly won’t be my last, she made me feel completely comfortable and at ease. She is incredibly professional, knowledgeable, and takes the time to really listen and understand what you want to achieve. Rachel has a very natural approach and her attention to detail is amazing. I feel confident knowing I’m in such skilled hands, and the results have been exactly what I hoped for. Thank you, Rachel, for your care, expertise, and for always making the whole experience so positive. I wouldn’t hesitate to recommend you to anyone looking for a trusted and talented practitioner.
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Laura Hilton
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What a lovely salon with lovely girls, I've just started to come here for my B12 and recently had anti wrinkle treatment, Rachel has been very kind and informative and made me feel at ease when having the treatment, the treatment looks really really good, only took two days to notice the difference, I would highly recommend Rachel to anyone who is looking to look good and feel good about themselves, good price, great location. Thanks Rachel, I'll be back! Xx
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Jana Ohrimenko
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I recently had polynucleotide under-eye injections with Rachel, and I couldn’t be more pleased with both the experience and the results so far. From the moment I arrived, Rachel was incredibly welcoming, professional, and knowledgeable. She took the time to explain the treatment thoroughly and made me feel completely comfortable and reassured throughout the entire process. The treatment itself was surprisingly pain-free, with minimal discomfort and very little downtime afterwards. I’ve already noticed a significant improvement in the appearance of my under-eye area - it looks brighter, more refreshed, and the fine lines have softened noticeably. As someone who works night shifts in the NHS, tired-looking eyes have always been a concern for me, so seeing such positive results already has been amazing. I’m excited to complete the rest of my treatment course and see the full benefits. I would highly recommend Rachel to anyone considering polynucleotide treatments. Her professionalism, expertise, and friendly approach make the whole experience exceptional ❤️
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Sarah Joyce profile picture
Sarah Joyce
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Had Botox in 3 areas and very happy with results. Rachel is very professional and made me feel comfortable and relaxed. I will definitely be returning. Thankyou Rachel
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Steph Barton
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I received a really warm welcome and everything was explained; the why and how which put me at ease. The treatment was quick and the aftercare was great. Messages were always replied to quickly if I had any questions :) Thankyou!!!
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Holly Alexandra Pimlott
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I recently had my Botox done with Rachel & wow! I am so impressed with my results. I had 3 areas and she’s done an amazing job. She is extremely professional, she listens to exactly what you want & advises you also. She is very gentle when injecting and completely puts you at ease. Thank you Rachel, I can’t wait for my next treatments with you.
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Freya Holt
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Rachel is a magician, didn’t even need a top up… what more can I say ⭐️⭐️⭐️⭐️⭐️
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Alice Atkinson profile picture
Alice Atkinson
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Rach was so welcoming and helpful, made me feel so at ease. I’m soooo happy with my results!! Can’t wait to come back in the future! Xxx

Frequently Asked Questions (FAQ)

Skin boosters mainly hydrate. Polynucleotides go further, stimulating collagen and elastin so the skin repairs and regenerates rather than simply holding water.
They help with fine lines, dullness, uneven texture, under-eye fatigue, mild scarring and general skin laxity across the face, neck and décolletage.
Some brightness appears within a couple of weeks, but the regenerative effect builds gradually over the full course as collagen rebuilds.
Yes. They are highly purified, biocompatible and widely used in regenerative medicine and aesthetics with an excellent safety record.
We usually recommend a course of two to three sessions spaced three to four weeks apart, then maintenance every six to nine months.
Yes. The under-eye is one of the most popular areas, where polynucleotides improve skin quality and crepiness rather than filling a hollow.

Ready to feel your most confident?

Want healthier, stronger skin from within? Book a consultation and we will plan a polynucleotide course for your skin.

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Every regenerative treatment starts with a face-to-face consultation, where we look at your skin, talk through what you would like to improve and agree a plan that suits you. Your suitability is always confirmed first.

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