So I Hear You Have A Question...

Do Polynucleotides Actually Work?

So I Hear You Have A Question...

Do Polynucleotides Actually Work?

To Answer Your Question...

There is reasonable evidence that polynucleotides improve skin quality, hydration and firmness, particularly in thin or crepey skin around the eyes. They are a skin conditioning treatment rather than a filler, so they will not add volume or lift. Most people need a full course before the change becomes obvious.

The Deatils...

What the research points to

Polynucleotides are purified DNA fragments, usually derived from salmon, that are injected into the skin to encourage repair and hydration. Published studies are mostly small, but they consistently point the same way, towards better hydration, improved elasticity and a modest reduction in fine lines. That is a genuine effect rather than a marketing claim, and it is also a fairly modest one. Anyone promising a dramatic change from a single session is overselling it. Our page on how long polynucleotides take to work sets out the realistic timeline.

What they will not do

Polynucleotides do not add volume, so they will not build a cheek, sharpen a jawline or plump a lip. They will not lift loose skin, and they will not remove deep static lines that are already etched in. If your main concern is structure or sagging, this is not the treatment for it, and we would tell you that at consultation rather than sell you a course that cannot deliver. Being clear about the limits is part of why people come to us.

How to judge it for yourself

Take a photograph in natural light before you start, and take another in the same light six weeks after your final session. Skin quality changes are gradual, so memory is a poor guide and a photograph is not. Look at texture, at how the skin under the eye catches the light and at how makeup sits, rather than looking for a line to have vanished. Most people need a course of sessions before any of that is fair to assess.

To Summarise:

Polynucleotides work on skin quality rather than volume. Expect better hydration and texture over a course of sessions, not an instant or dramatic change.

Testimonials

    
 
 
         
   Lottie Hawthorn 
 
 
 
 Trustindex verifies that the original source of the review is Google. I would 100% recommend Rachel, she was very gentle whilst doing the treatment as well as being so welcoming and friendly on my first visit. The results where amazing and lasted months! 🤩
  
 
        
   Aimee Goertz 
 
 
 
 Trustindex verifies that the original source of the review is Google. Highly rate Rachael and her skin lounge. Rachael ensures to fully understand how you like to feel after your Botox before taking any action. I walked away feeling fabulous and knowing how much Racheal cares about how her clients look and feel! Thank you 🙏
  
 
        
   Jennie Hoskins 
 
 
 
 Trustindex verifies that the original source of the review is Google. I can’t recommend Rachel highly enough. This was my very first appointment with Rachel and it certainly won’t be my last, she made me feel completely comfortable and at ease. She is incredibly professional, knowledgeable, and takes the time to really listen and understand what you want to achieve.

Rachel has a very natural approach and her attention to detail is amazing. I feel confident knowing I’m in such skilled hands, and the results have been exactly what I hoped for.

Thank you, Rachel, for your care, expertise, and for always making the whole experience so positive. I wouldn’t hesitate to recommend you to anyone looking for a trusted and talented practitioner.
  
 
        
   Laura Hilton 
 
 
 
 Trustindex verifies that the original source of the review is Google. What a lovely salon with lovely girls, I've just started to come here for my B12 and recently had anti wrinkle treatment, Rachel has been very kind and informative and made me feel at ease when having the treatment, the treatment looks really really good, only took two days to notice the difference, I would highly recommend Rachel to anyone who is looking to look good and feel good about themselves, good price, great location. Thanks Rachel, I'll be back! Xx
  
 
        
   Jana Ohrimenko 
 
 
 
 Trustindex verifies that the original source of the review is Google. I recently had polynucleotide under-eye injections with Rachel, and I couldn’t be more pleased with both the experience and the results so far.

From the moment I arrived, Rachel was incredibly welcoming, professional, and knowledgeable. She took the time to explain the treatment thoroughly and made me feel completely comfortable and reassured throughout the entire process.

The treatment itself was surprisingly pain-free, with minimal discomfort and very little downtime afterwards. I’ve already noticed a significant improvement in the appearance of my under-eye area - it looks brighter, more refreshed, and the fine lines have softened noticeably.

As someone who works night shifts in the NHS, tired-looking eyes have always been a concern for me, so seeing such positive results already has been amazing. I’m excited to complete the rest of my treatment course and see the full benefits.

I would highly recommend Rachel to anyone considering polynucleotide treatments. Her professionalism, expertise, and friendly approach make the whole experience exceptional ❤️
  
 
        
   Sarah Joyce 
 
 
 
 Trustindex verifies that the original source of the review is Google. Had Botox in 3 areas and very happy with results. Rachel is very professional and made me feel comfortable and relaxed.
I will definitely be returning.
Thankyou Rachel
  
 
        
   Steph Barton 
 
 
 
 Trustindex verifies that the original source of the review is Google. I received a really warm welcome and everything was explained; the why and how which put me at ease. The treatment was quick and the aftercare was great. Messages were always replied to quickly if I had any questions :) Thankyou!!!
  
 
        
   Holly Alexandra Pimlott 
 
 
 
 Trustindex verifies that the original source of the review is Google. I recently had my Botox done with Rachel & wow! I am so impressed with my results. I had 3 areas and she’s done an amazing job. She is extremely professional, she listens to exactly what you want & advises you also. She is very gentle when injecting and completely puts you at ease. Thank you Rachel, I can’t wait for my next treatments with you.
  
 
        
   Freya Holt 
 
 
 
 Trustindex verifies that the original source of the review is Google. Rachel is a magician, didn’t even need a top up… what more can I say ⭐️⭐️⭐️⭐️⭐️
  
 
        
   Alice Atkinson 
 
 
 
 Trustindex verifies that the original source of the review is Google. Rach was so welcoming and helpful, made me feel so at ease. I’m soooo happy with my results!! Can’t wait to come back in the future! Xxx

Frequently Asked Questions (FAQ)

Are polynucleotides worth the money?

That depends on what bothers you. If it is dull, thin or crepey skin, most people feel the course was worthwhile. If it is volume loss or sagging, it is not the right spend, and we would say so at consultation rather than take the booking.

Do polynucleotides work on everyone?

No treatment works for everyone. Response varies with age, skin condition, smoking and general health, and some people notice less than others. We assess your skin first and give you an honest view of what is likely, rather than a guarantee.

Is one brand more effective than another?

The differences between products are smaller than the marketing suggests, and technique and treatment plan matter more. Our guide to polynucleotide brands in the UK explains what genuinely separates them.

Ready To Feel Your Most Confident?

If you want an honest view on whether polynucleotides suit your skin, book a consultation with our Southport clinic and we will tell you either way.

how long polynucleotides take to work

how many sessions you need

polynucleotide brands in the UK

Request A Consultation

Request an appointment using the form below and one of our team members will get back to you as soon as possible.

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Every polynucleotide appointment at The Skin and Aesthetics House begins with a consultation, where we look at your skin, go through your medical history and agree whether this is the right treatment for you before anything goes ahead.

So I Hear You Have A Question...

Do Polynucleotides Actually Work?

So I Hear You Have A Question...

Do Polynucleotides Actually Work?

To Answer Your Question...

The Deatils...

What the research points to

What they will not do

How to judge it for yourself

To Summarise:

Testimonials

Frequently Asked Questions (FAQ)

Ready To Feel Your Most Confident?

Related Pages:

how long polynucleotides take to work

how many sessions you need

polynucleotide brands in the UK

Request A Consultation

Request A Consultation

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